Comparing NMR and X-ray protein structure: Lindemann-like parameters and NMR disorder

NMR studies of protein structure and dynamics.

Recent advances in solution NMR spectroscopy have significantly extended the spectrum of problems that can now be addressed with this technology. In particular, studies of proteins with molecular weights on the order of 100 kDa are now possible at a level of detail that was previously reserved for much smaller systems. An example of the sort of information that is now accessible is provided in ...

Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2.

Metallothioneins are small cysteine-rich proteins capable of binding heavy metal ions such as Zn2+ and Cd2+. They are ubiquitous tissue components in higher organisms, which tentatively have been attributed both unspecific protective functions against toxic metal ions and highly specific roles in fundamental zinc-regulated cellular processes. In this paper a detailed comparison of the NMR solut...

NMR studies of protein dynamics and structure

................................................................................................... 9 Introduction............................................................................................. 10 Aim of this thesis........................................................................................................ 10 Adenylate kinase...............................................

Automated NMR protein structure calculation

Nmr Investigations of Protein Structure